CLIA NT-proBNP
Chemiluminescence kit for the detection of Nt-proBNP in human serum and heparine plasma.
Coming soon
Chemiluminescence kit for the detection of Nt-proBNP in human serum and heparine plasma.
| Catalog Number: | CL-NTpBNP100 |
|---|---|
| Size: | 100 tests |
| Clinical topic: | Cardiovascular Diseases & Salt Metabolism |
NT-proBNP concentration is a quantitative plasma biomarker for the presence and severity of hemodynamic cardiac stress and heart failure (HF). Current guidelines for the diagnosis and management of heart failure recommend the use of NT-proBNP as an established biomarker for HF diagnosis, therapy monitoring, and prognosis and implemented it in algorithms for the diagnosis and treatment of HF. The measurement NT-proBNP is helpful in screening to identify or exclude cardiac disease and is also a robust powerful prognostic tool. It can help clinicians to establish the differential diagnosis of symptoms that might be due to HF and manage patients in several clinical scenarios.
Diagnosis of Heart Failure
The most common presentation of HF is dyspnea and fatigue, complaints that are neither specific nor sensitive for predicting the presence of HF. NT-proBNP is an essential initial investigation to improve diagnostic accuracy and facilitate early diagnosis or the early exclusion of HF in both acute and non-acute settings.
Risk Stratification and Outcome Prediction
Measurement of NT-proBNP is useful to establish a prognosis of disease severity in chronic HF. On admission to the hospital, it is useful for prognosis in acutely decompensated HF. During an HF hospitalization, a predischarge NT-proBNP level can be used to establish a postdischarge prognosis.
Monitoring and prevention
NT-proBNP biomarker is also utilized in CHF disease and treatment monitoring and new data suggest that NT-proBNP screen and early intervention may prevent HF.
| Assay time | 25 min |
| Assay stability | 30 days on board stability / In use stability until the expiration date at storage temperature 2-8 °C |
| Sample matrix | Serum, Plasma-Heparin |
| Sample volume | 40 µL |
| Sample stability | 7 days at 2-8 °C, 24 months at -20 °C |
| Measuring range | 125 – 8000 pg/ml |
| Assay/kit content | Reagent Cartridge with specific reagents for the assay, magnetic particles, calibrators |
| Complementary products | Wash buffer, Anchor® Tips, Stackable cuvettes, Trigger solutions |
